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124 Randomized, Clinical Trial of Ligasure™ vs. Conventional Diathermy in Hemorrhoidectomy [2003년 10월 DCR] 2011-11-17 3609
 
Ernest J. Franklin, M.D.,* Seema Seetharam, M.R.C.S.,† Jennifer Lowney, M.D.,*Paul G. Horgan,Ph.D.†

From *Barnes Hospital, Washington University School of Medicine, St. Louis, Missouri, and the Academic Department of Surgery, Glasgow Royal Infirmary, Glasgow, United Kingdom
 
PURPOSE: Hemorrhoidectomy is frequently associated with significant postoperative pain, and new techniques to reduce this pain are constantly under evaluation. The present study was conducted to determine the usefulness of the Ligasure™ system and compare it with conventional diathermy for hemorrhoidectomy.
METHODS: Thirty-four consecutive patients with Grade 3 or 4 hemorrhoids requiring surgery were recruited and randomized into two groups by preoperative assignment of sealed envelopes. Patients with coexisting perianal disease, previous perianal surgery, or thrombosed hemorrhoids were excluded. All patients were anesthetized and operated on by a single team. In one group, monopolar diathermy in the coagulation mode was used to dissect hemorrhoidal tissue from the internal sphincter. In the second group, tissue was coagulated by Ligasure™ and then divided with scissors. Operating time was documented by theater staff. Postoperatively, pain scores and Cleveland Clinic incontinence scores were documented.
RESULTS: Seventeen patients were randomized into each group. There were no significant differences in age, gender, or clinical symptoms between the groups. The mean operating time in the Ligasure™ group was 6 (range, 4–10) minutes compared with 11 (range, 7–20) minutes in the other group, and this was statistically significant (P < 0.001). Patients in the Ligasure™ group reported significantly less pain with first defecation and at postoperative Days 1 and 14 (P < 0.001). The mean hospital stay in both
groups was one (range, 1–5) day, and there was no difference in the incontinence scores.
CONCLUSIONS: Ligasure ™ diathermy provides a superior alternative to conventional diathermy in hemorrhoidectomy by reducing operating time and postoperative pain.